Comorbidity of Glucose-6-Phosphate Dehydrogenase Deficiency and Sickle Cell Disease Exert Significant Effect on RBC Indices
Background.Glucose-6-phosphate dehydrogenase (G6PD) converts glucose-6-phosphate into 6-phosphogluconate in the pentose phosphate pathway and protects red blood cells (RBCs) from oxidative damage.Their deficiency therefore makes RBCs prone to haemolysis.Sickle cell disease (SCD) on the other hand is a hereditary blood disorder in which there is a s